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Results for "

INCB 18424

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

2

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-50856
    Ruxolitinib
    120+ Cited Publications

    INCB18424

    		 JAK Autophagy Mitophagy Apoptosis Cancer
    Ruxolitinib (INCB18424) is a potent and selective JAK1/2 inhibitor with IC50s of 3.3 nM and 2.8 nM in cell-free assays, and has 130-fold selectivity for JAK1/2 over JAK3 . Ruxolitinib induces autophagy and kills tumor cells through toxic mitophagy .
    Ruxolitinib
  • HY-50856A
    Ruxolitinib (S enantiomer)
    4 Publications Verification

    S-Ruxolitinib; S-INCB18424

    		 JAK Cancer
    Ruxolitinib (S enantiomer) (S-Ruxolitinib) is the S-enantiomer of Ruxolitinib (HY-50856). Ruxolitinib (S enantiomer) is an orally active, potent JAK inhibitor .
    Ruxolitinib (S enantiomer)
  • HY-W062703S1
    (Rac)-Ruxolitinib-d8

    (Rac)-INCB18424-d8; Ruxotinib racemate-d8

    		 Isotope-Labeled Compounds Others
    (Rac)-Ruxolitinib-d8 is deuterium labeled (Rac)-Ruxolitinib.
    (Rac)-Ruxolitinib-d8
  • HY-W062703S
    (Rac)-Ruxolitinib-d9

    (Rac)-INCB18424-d9; Ruxotinib racemate-d9

    		 Isotope-Labeled Compounds JAK Cancer
    (Rac)-Ruxolitinib D9 ((Rac)-INCB18424 D9) is the deuterium labeled (Rac)-Ruxolitinib. (Rac)-Ruxolitinib is a JAK2 inhibitor .
    (Rac)-Ruxolitinib-d9
  • HY-50856R
    Ruxolitinib (Standard)

    		Cancer
    Ruxolitinib (Standard) is the analytical standard of Ruxolitinib. This product is intended for research and analytical applications. Ruxolitinib (INCB18424) is a potent and selective JAK1/2 inhibitor with IC50s of 3.3 nM and 2.8 nM in cell-free assays, and has 130-fold selectivity for JAK1/2 over JAK3 . Ruxolitinib induces autophagy and kills tumor cells through toxic mitophagy .
    Ruxolitinib (Standard)

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